Pharmaceuticals Efficacy Testing
Pharmaceutical preparations with inadequate
anti-microbial activity are likely to have anti-microbial
preservatives added. These additives are designed to prevent
proliferation or limit contamination by micro-organisms. The
preservative qualities of the preparation are checked during
development by performance of an Efficacy of Anti-microbial
Preservation Test.
During the development of pharmaceutical
preparations, it is necessary to prove that the anti-microbial
activity of the preparation is adequate to prevent the problems
that could occur from microbial contamination or proliferation
during storage.
The BP, EP and USP detail guidance on the
performance and interpretation of preservative efficacy testing.
Our in-house method, which is UKAS accredited,
has been developed according to the Ph. Eur. We can, however,
perform testing according to the BP or USP.
The types of preparations for testing range
from powders through to liquids and include topical creams,
oral syrups and parenteral solutions.
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